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ALS Northwest Boosts 2025 Research Funding Through ALS United Collaboration to Accelerate ALS Breakthroughs

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ALS Northwest Wraps 2025 With a Bigger Bet on Research — and a Message of Urgency for Families

SHERIDAN, WYOMING - December 30, 2025 - ALS Northwest says it increased its financial investment in ALS research throughout 2025, expanding support for new approaches in treatment, prevention, and scientific understanding while joining a multi-organization funding initiative intended to strengthen the overall research pipeline.

Research investment strategy and portfolio focus

ALS Northwest framed its 2025 approach as a scaled-up commitment to research designed to accelerate innovation in amyotrophic lateral sclerosis (ALS). The organization said its efforts span multiple stages of scientific discovery, with an emphasis on enabling new approaches that could move the field forward. For research stakeholders, the operational question is not only how much is invested, but how efficiently funding is converted into validated findings, new targets, and ultimately clinical progress.

PSEG Long Island Secures LIPA Operating Contract Extension as New Leadership Takes Charge

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PSEG Long Island Secures LIPA Operating Contract Extension as New Leadership Takes Charge

SHERIDAN, WYOMING - December 30, 2025 - Public Service Enterprise Group (PSEG) says New York State's comptroller has granted final approval for an extension of PSEG Long Island's operations services agreement with the Long Island Power Authority (LIPA), locking in continued grid-operations responsibilities through the end of 2030.

Contract extension now fully cleared

PSEG said the LIPA Board of Trustees awarded PSEG Long Island a five-year extension of the existing contract on September 25, followed by approval from the New York State attorney general in October and final approval from the comptroller this week. The extension begins January 1, 2026, and runs through December 31, 2030. PSEG Long Island has operated the electric grid on behalf of LIPA since 2014, covering Long Island and the Rockaways.

Yokohama's GEOLANDAR X-CV Targets Premium EV SUV Segment with New Lexus RZ Fitment in North America

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Yokohama’s GEOLANDAR X-CV Targets Premium EV SUV Segment with New Lexus RZ Fitment in North America

SHERIDAN, WYOMING - December 26, 2025 - Yokohama Rubber is sharpening its focus on electric-vehicle OEM business in the automotive & mobility sector, confirming that its GEOLANDAR X-CV highway terrain tire is now factory-equipped on the newly updated Lexus RZ battery-electric SUV for the North American market. The 235/50R20 100V fitment positions Yokohama's SUV-focused GEOLANDAR line squarely in the premium BEV arena, supporting automakers' push for quieter, more efficient and more durable EV drivetrains.

Premium EV SUV fitment strengthens North American footprint

Yokohama Rubber and RAOT Expand Thai Farmer Training to Safeguard Sustainable Natural Rubber Supply

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Yokohama Rubber and RAOT Expand Thai Farmer Training to Safeguard Sustainable Natural Rubber Supply

SHERIDAN, WYOMING - December 26, 2025 - Yokohama Rubber and Thailand's Rubber Authority (RAOT) have reached a new milestone in their long-term partnership to secure sustainable natural rubber, completing their tenth joint seminar to help smallholder farmers in Surat Thani improve rubber quality, productivity and working conditions across the supply chain.

Supporting smallholders at the heart of the rubber supply chain

The latest seminar, held in December 2025, brought together around 50 farming households from the Surat Thani region, one of Thailand's core natural rubber-producing areas and home to Yokohama Rubber's processing subsidiary Y.T. Rubber Co., Ltd. The program focused on practical measures to improve yield and quality at farm level, a critical factor for tire makers who depend on consistent, traceable natural rubber as a key raw material.

Yokohama Rubber Realigns Senior Leadership to Accelerate Production, R&D and Asia Expansion

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Yokohama Rubber Realigns Senior Leadership to Accelerate Production, R&D and Asia Expansion

SHERIDAN, WYOMING - December 26, 2025 - The Yokohama Rubber Co., Ltd. is reshaping its senior leadership structure from January 1, 2026, sharpening its focus on tire production efficiency, advanced materials development, and growth in China and Asia across both tire and industrial product lines. The new appointments consolidate operational responsibility around key associates, signaling a push toward tighter coordination between manufacturing, R&D and regional business development.

Strengthening leadership around tire production and investment planning

ADVAN Tires Star in "Gymkhana: Aussie Shred" as Yokohama Accelerates its High-Value Performance Strategy

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ADVAN Tires Star in “Gymkhana: Aussie Shred” as Yokohama Accelerates its High-Value Performance Strategy

SHERIDAN, WYOMING - December 26, 2025 - Yokohama Rubber is leveraging the global reach of the Gymkhana stunt-film franchise to spotlight its ADVAN flagship performance tires, with the latest episode "Gymkhana: Aussie Shred" showcasing ADVAN-equipped Subaru machinery and racking up more than 5.3 million views in its first week online.

ADVAN brand visibility in a high-impact global stunt platform

The new film, released on Hoonigan Media Machine's official YouTube channel on December 9, 2025, is the third consecutive Gymkhana installment to feature ADVAN tires as original equipment on the lead vehicle.
Co-produced by Hoonigan Media Machine, 321 Action Action and Subaru Motorsports USA, the series has become a global benchmark for extreme driving content, delivering sustained visibility for tire and performance brands among highly engaged enthusiasts.

Yokohama Rubber Backs International Initiative to Protect Natural Rubber Supply and Smallholder Livelihoods

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Yokohama Rubber Backs International Initiative to Protect Natural Rubber Supply and Smallholder Livelihoods

SHERIDAN, WYOMING - December 26, 2025 - Yokohama Rubber is deepening its sustainability strategy and raw materials risk management by supporting an international joint research project in Indonesia aimed at preventing rubber tree leaf fall diseases, a growing threat to global natural rubber production and the tire industry's long-term resilience.

Securing Natural Rubber at the Source in Indonesia

The company is cooperating in the multi-year project "Development of Complex Technologies for Prevention and Control of Rubber Tree Leaf Fall Diseases," which targets one of the most serious plant health challenges facing natural rubber plantations in Indonesia, the world's second-largest producer.
Leaf fall disease has become widespread in key growing regions, leading to significant yield losses and jeopardizing supply for industrial users, including tire manufacturers.

Yokohama AVID GT Selected as OEM Tire for New Nissan LEAF, Advancing EV-Focused Tire Strategy

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Yokohama AVID GT Selected as OEM Tire for New Nissan LEAF, Advancing EV-Focused Tire Strategy

SHERIDAN, WYOMING - December 26, 2025 - Yokohama Rubber has expanded its presence in the electric vehicle supply chain as Nissan chooses the AVID GT as original equipment for the new Nissan LEAF in the United States, underlining the growing role of EV-optimized tire technology in improving range, comfort and safety for mainstream electric cars.

EV-Optimized Tires for a Core Mass-Market Electric Vehicle

Yokohama Rubber has begun supplying its AVID GT in size 215/55R18 95H as factory equipment for the latest Nissan LEAF EV launched in the U.S. market in 2025. Positioned as a key electric model for drivers transitioning from internal combustion engines to battery-electric vehicles, the new LEAF benefits from a tire package specifically engineered to support higher curb weights, instant torque and demanding efficiency targets.

Yokohama Rubber Wins OE Slot on Nissan's New Roox with BluEarth-FE AE30 Eco Tire

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Yokohama Rubber Wins OE Slot on Nissan’s New Roox with BluEarth-FE AE30 Eco Tire

SHERIDAN, WYOMING - December 26, 2025 - Yokohama Rubber is strengthening its position in Japan's highly competitive mini-vehicle segment as it begins supplying its fuel-efficient BluEarth-FE AE30 tire as original equipment for Nissan's new Roox, launched in 2025 and equipped in selected grades with 155/65R14 75S fitments.

Fuel-efficient OE tire for Japan's next-generation kei car

The OE deal places Yokohama's BluEarth-FE AE30 at the heart of one of Japan's most important volume segments: compact, city-focused mini-vehicles. Built under the BluEarth brand concept of being "environmentally, human, and socially friendly," the BluEarth-FE AE30 is positioned as a standard tire that balances rolling resistance, safety and comfort - critical factors for OEMs seeking to meet fuel-efficiency regulations and customer expectations in urban use.

du and Huawei Bring 25Gbps E-Band Backhaul to 5G-Advanced Rollout in the UAE

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du and Huawei Bring 25Gbps E-Band Backhaul to 5G-Advanced Rollout in the UAE

SHERIDAN, WYOMING - December 24, 2025 - UAE operator du has signed a three-year agreement with Huawei after deploying what the companies describe as the world's first 25Gbps E-band microwave link to support a 5G-Advanced (5G-A) site rollout, aiming to boost capacity and consistency where fiber backhaul is limited.

From "site upgrades" to backhaul strategy
5G-Advanced pushes more traffic through the radio layer, but the customer experience still hinges on the transport network behind it. du framed the partnership as a joint innovation framework-not just procurement-designed to keep pace with surging data transmission demand while accelerating scalable 5G-A coverage across the UAE, including areas where fiber deployment is slower or impractical.

BMS Signs $1B-Plus Multi-Specific Antibody Pact With China's Harbour BioMed

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BMS Signs $1B-Plus Multi-Specific Antibody Pact With China’s Harbour BioMed

SHERIDAN, WYOMING - December 19, 2025 - Bristol Myers Squibb (BMS) has struck a potential $1B-plus partnership with Harbour BioMed to collaborate on next-generation multi-specific antibody programs, underscoring how China-based innovation is increasingly shaping global biologics dealmaking.

Deal scope and economics in brief
BMS will pay $90 million upfront to work with Harbour on developing and advancing multi-specific antibody therapies, with additional development and commercial milestones that could total up to $1.035 billion. The partners did not disclose how many programs are covered, nor did they specify initial targets, indications, or therapeutic areas.

For business development teams and portfolio planners, the structure reflects a familiar "platform-plus-programs" model: BMS buys early discovery leverage and optionality, while Harbour positions itself for milestone upside and downstream royalties if programs progress.

Voyager Cuts 30 Roles After Novartis Drops Two Early Gene Therapy Programs

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Voyager Cuts 30 Roles After Novartis Drops Two Early Gene Therapy Programs

SHERIDAN, WYOMING - December 19, 2025 - Voyager Therapeutics is laying off 30 employees after partner Novartis discontinued two undisclosed discovery-stage programs under the companies' gene therapy collaboration, underscoring how quickly platform-driven R&D bets can be reprioritized even inside marquee pharma partnerships.

Commercial partnerships can shift overnight
Voyager disclosed last month that Novartis had stepped away from two early programs tied to their ongoing relationship, without naming the assets or detailing the rationale. The biotech framed the change as manageable, stating that Novartis' decision will "not impact Voyager's cash runway guidance." Still, the workforce reduction signals that operational resets often follow partnership scope changes-especially when programs are preclinical and the near-term value is concentrated in a smaller set of advancing assets.

Phase 3 KEYNOTE-B15 Puts KEYTRUDA-Padcev on Track to Redefine Perioperative Care in Muscle-Invasive Bladder Cancer

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Merck’s KEYTRUDA Plus Padcev Posts Phase 3 Perioperative Win in Cisplatin-Eligible Muscle-Invasive Bladder Cancer

SHERIDAN, WYOMING - December 19, 2025 - Merck reported positive topline Phase 3 data showing its immunotherapy KEYTRUDA (pembrolizumab) combined with the antibody-drug conjugate Padcev (enfortumab vedotin-ejfv) improved event-free survival, overall survival and pathologic complete response when used before and after surgery in cisplatin-eligible muscle-invasive bladder cancer (MIBC), setting up a potential shift in the perioperative standard of care.

Merck Secures Positive CHMP Opinion to Expand WINREVAIR Use in PAH, Potentially Extending Treatment to WHO FC IV in Europe

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Merck Secures Positive CHMP Opinion to Expand WINREVAIR Use in PAH, Potentially Extending Treatment to WHO FC IV in Europe

SHERIDAN, WYOMING - December 19, 2025 - Merck said the EMA's CHMP has recommended approval of an expanded European indication for WINREVAIR (sotatercept) in adults with pulmonary arterial hypertension (PAH), a move that-if confirmed by the European Commission-could broaden use to include WHO Functional Class (FC) IV patients and strengthen the product's positioning around morbidity and mortality benefit.

EXZOLT CATTLE-CA1 Wins FDA Conditional Approval, Expanding Options to Prevent and Treat New World Screwworm in Cattle

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FDA Conditionally Approves Merck Animal Health’s EXZOLT CATTLE-CA1 to Address New World Screwworm Risk in U.S. Beef and Heifer Herds

SHERIDAN, WYOMING - December 19, 2025 - Merck Animal Health says the U.S. Food and Drug Administration (FDA) has granted conditional approval for EXZOLT™ CATTLE-CA1 (fluralaner topical solution), positioning the pour-on as a new systemic parasiticide option for U.S. beef operations and replacement dairy heifers facing New World screwworm (Cochliomyia hominivorax) larvae (myiasis) risk and cattle fever tick (Rhipicephalus microplus) pressure.

FDA Weighs National Priority Vouchers for Merck's Enlicitide and Sacituzumab Tirumotecan, Potentially Compressing Review Timelines

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FDA Weighs National Priority Vouchers for Merck’s Enlicitide and Sacituzumab Tirumotecan, Potentially Compressing Review Timelines

SHERIDAN, WYOMING - December 19, 2025 - The FDA is considering awarding Commissioner's National Priority Vouchers to two investigational Merck programs-PCSK9 pill enlicitide decanoate and antibody-drug conjugate sacituzumab tirumotecan-an early signal that the agency may be willing to accelerate reviews for high-impact products even before formal filings, according to a Reuters report.

A new FDA lever that can reshape launch timing
Commissioner's National Priority Vouchers are designed to shorten the FDA's regulatory review window from the typical 10-12 months to 1-2 months. For large pharma, that time compression can meaningfully shift competitive dynamics-pulling forward commercialization, altering payer and guideline sequencing, and increasing the urgency of manufacturing readiness, launch supply, and field execution.

Dentrix Ascend Adoption Surges as DSOs and Multi-Site Dental Groups Push Deeper Into Cloud and AI

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Henry Schein One's Dentrix Ascend Gains Momentum as 600 Practices Migrate in 2025 and DSO Adoption Accelerates

SHERIDAN, WYOMING - December 19, 2025 - Henry Schein One says adoption of its cloud-native Dentrix Ascend platform is accelerating as dental groups and DSOs move away from legacy practice management systems to standardize operations, reduce administrative friction, and embed AI into everyday workflows.

Cloud migration becomes a scaling decision, not an IT project
Across U.S. dentistry, consolidation and multi-location growth are forcing operators to treat practice management software as core infrastructure. Henry Schein One reported that nearly 600 practices migrated from alternative systems to Ascend over the past 12 months, adding to the broader Dentrix customer base of more than 48,000 practices using Dentrix technology for clinical, operational, and financial workflows. The company also said monthly Ascend installations more than doubled year over year as practices transitioned away from legacy setups.