Rice-Backed Duracyte to Trial Implant That Makes Drugs Inside Body
Houston – October 02, 2026 -- Researchers at Rice University, backed by the Rice Biotech Launch Pad, have developed an implantable device that produced therapeutic monoclonal antibodies continuously for one year across multiple preclinical models, with the platform now advancing toward human trials through biotech company Duracyte.
Implant sustained antibody production for a full year in preclinical testing
The system, detailed in a study published in Science Advances titled "Once-yearly cell-based therapy for sustained and dose-tunable delivery of monoclonal antibodies," uses engineered protein producers (EPPs) enclosed in a modified biomaterial. The retrievable device also let researchers halt treatment or adjust dosing by removing or replacing the implant, addressing the foreign body response -- inflammation and scar tissue buildup -- that typically limits implanted cell therapy performance.