Oncology Drug Development

BOSTON – October 30, 2026 -- Medicilon presented Revolution Medicines, Inc. with its "Excellence in Client Partnership Award" after more than three years of joint work on pan-KRAS drug discovery, following the U.S. FDA's August 2026 approval of the NDA for Daraxonrasib in metastatic pancreatic cancer.

Dr. Yang Liu, Director of Medicinal Chemistry at Revolution Medicines, and Senior Scientist Dr. Kristof Pota received the award during a visit to Medicilon's Nanhui R&D Center. Dr. Maosheng Duan, President of Medicilon's Drug Discovery and Pharmaceutical Research Divisions, and Dr. Jian Wang, Vice President, hosted the delegation.

TAMPA – October 27, 2026 -- Akari Therapeutics (Nasdaq: AKTX) is targeting a First-In-Human trial of its lead antibody drug conjugate (ADC), AKTX-101, by mid-2027, after starting IND-enabling studies. The company laid out its investment case in the Virtual Investor "Why Now" on-demand conference.

CEO Abizer Gaslightwala argued that now is a pivotal time for Akari. He cited a fast-changing ADC landscape and rising industry demand for differentiated payload technologies.

Akari pitches PH1 splicing payload as alternative to conventional ADC toxins

Akari's proprietary PH1 platform is a spliceosome modulator designed to disrupt RNA splicing inside cancer cells. Current ADCs rely on microtubule inhibitors and DNA-damaging agents. According to the company, PH1 is meant to address limitations of those conventional payloads.