SHERIDAN, WYOMING - November 25, 2025 - Royal Philips is introducing DeviceGuide, an AI-powered device tracking solution that brings real-time, 3D navigation support into one of interventional cardiology's most demanding procedures: minimally invasive repair of leaking heart valves. Built on the company's EchoNavigator platform and previewed at London Valves 2025, DeviceGuide is designed to translate complex imaging into intuitive visual guidance, helping structural heart teams perform mitral valve repair with greater clarity, confidence and reproducibility.
AI-guided navigation inside the procedure room
The new solution is aimed squarely at one of the most challenging aspects of transcatheter structural heart interventions: steering tiny repair devices through a beating heart while working from multiple imaging sources. DeviceGuide uses an AI algorithm to automatically track the miniature repair device as it moves, combining live echo and X-ray images and generating a virtual 3D model of the device in real time.
"With DeviceGuide, we're bringing AI into the heart of the procedure room, and into the heart itself," said Dr. Atul Gupta, Chief Medical Officer, Diagnosis & Treatment at Philips. "This is Philips' first AI assisting physicians in real time to visualize and guide heart valve treatment devices* as they navigate the beating heart. It's helping doctors in the moment as they are helping their patients with structural heart disease."
For interventional cardiologists, the result is a clearer understanding of where the device is, how it is oriented and how it is interacting with moving valve leaflets - information that can support more precise navigation and deployment during high-stakes mitral repair procedures.
Tackling mitral valve regurgitation in high-risk patients
DeviceGuide is focused on improving outcomes in minimally invasive treatment of mitral valve regurgitation, a condition that affects more than 35 million adults worldwide and can leave patients short of breath, fatigued and struggling with basic daily activities. In severe cases, untreated regurgitation can lead to heart failure and other serious complications.
For patients considered too frail for open-heart surgery, minimally invasive transcatheter techniques such as mitral transcatheter edge-to-edge repair (M-TEER) offer a crucial alternative. These interventions are technically complex: teams must access the heart via a small incision in the groin, maneuver long, flexible instruments through blood vessels, and guide a tiny repair device into the beating heart to grasp the mitral leaflets and seal the leak.
Clinicians must continuously interpret X-ray and ultrasound images, coordinate movements between operators, and confirm device position and effectiveness in real time. By adding 3D device tracking and visualization to this environment, DeviceGuide is intended to support the high level of accuracy and coordination required.
How AI turns multimodality imaging into "bionic vision"
The system's AI model continuously analyzes live echo and fluoroscopy, automatically detecting and tracking the repair device. It then renders a 3D representation of the device and overlays this on the live images of the beating heart. This helps clinicians:
- See the device's position and orientation at a glance
- Maintain spatial awareness as views and angulations change
- Navigate more intuitively during leaflet grasping and deployment
- Confirm device placement and result more efficiently
"By embedding AI into the procedure, DeviceGuide gives physicians an extra pair of eyes, effectively bionic vision, helping them treat more patients safely and confidently.
- Dr. Atul Gupta, Chief Medical Officer, Diagnosis & Treatment at Philips
"The AI software serves as an assistive tool, with the physician always remaining in control. This isn't about replacing expertise - it's about amplifying it," added Dr. Atul Gupta. "By embedding AI into the procedure, DeviceGuide gives physicians an extra pair of eyes, effectively bionic vision, helping them treat more patients safely and confidently."
Designed around the mitral TEER workflow with Edwards Lifesciences
DeviceGuide was developed in close collaboration with Edwards Lifesciences, manufacturer of the mitral repair devices used in these procedures. The goal was not only to add AI capability, but to rethink specific steps in the mitral TEER workflow around how teams actually work in the lab.
"DeviceGuide demonstrates the impact of combining leading imaging and therapy expertise to develop solutions designed around the procedural workflow, a model that will shape the future of AI-enabled image-guided structural interventions," said Mark Stoffels, Business Leader, Image Guided Therapy Systems.
By combining Philips' strengths in medical imaging and AI with Edwards' therapy expertise, DeviceGuide illustrates a partnership model that could shape future AI-enabled, image-guided therapies across other structural heart indications.
Strategic implications for structural heart programs
For hospitals and heart centers, solutions like DeviceGuide point to a broader shift in structural heart care, where real-time AI support becomes a standard part of complex image-guided procedures. Potential benefits for forward-looking programs include:
- Enhanced confidence and consistency in technically demanding mitral TEER cases
- More intuitive team communication around device position and orientation
- Shorter learning curves for newer operators working with experienced teams
- A scalable model for bringing AI into other structural interventions
This innovation reinforces Philips' strategy of embedding AI directly into image-guided therapy systems to support clinicians "in the moment" of care, rather than adding standalone tools outside the core workflow.
To learn more about Philips DeviceGuide and its role in AI-enabled, image-guided structural heart interventions, visit https://www.philips.com/healthcare.