Healthcare, Pharma & Life Sciences

Chanhassen – October 28, 2026 -- Every patient with investigator-assessed clinical deterioration in an exploratory 15-patient glioblastoma analysis showed sustained increases in lactate dehydrogenase (LDH) during treatment, Alpheus Medical, Inc. reported at the ESMO Congress 2026 in Madrid.

Poster 4289P tracks LDH trajectories in 15 recurrent glioblastoma patients

The clinical-stage oncology company presented the data from its first-in-human study of Porphyrin Metabolite Activation (PoMA). The cohort comprised 15 patients with MGMT-unmethylated recurrent glioblastoma. Instead of relying on a single LDH value, the analysis examined how LDH changed over time and how those trajectories related to clinical and radiographic disease status.

Danbury – October 28, 2026 -- CellsBin has received a Direct-to-Phase II Small Business Innovation Research (SBIR) award from the National Cancer Institute (NCI) to advance CB-Insight, its blood-based test for multiple myeloma, a cancer of plasma cells in the bone marrow.

Federal award follows 108 BioCapital-led Series A

The NCI funding comes after CellsBin's Series A financing, announced in September and led by 108 BioCapital. Together, the private and federal money moves the myeloma program beyond early proof-of-concept work and into formal patient testing and development of a test that can be offered to doctors.

CellsBin first presented early myeloma results at the 2024 American Society of Hematology Annual Meeting. Privately funded work since then made the company eligible for the Direct-to-Phase II track, which lets small businesses that have already shown feasibility skip the Phase I stage.

PLEASANTON, Calif. – October 28, 2026 -- Altamont Software has made CaptureWare Video, its enterprise medical video capture solution, available on iPhone and iPad. Providers can now record medical video and still images at the bedside, in the clinic and at other point-of-care locations without a desktop computer.

Mobile devices connect to any scope through a low-cost USB capture card

A phone or tablet can be linked to any scope via a USB capture card, which Altamont says removes the need for a desktop computer or costly video connection box. The app forwards captured clinical images and video to PACS, VNA and the EMR. It also integrates medical video directly into Epic Lumens.

CHICAGO – October 28, 2026 -- 5th Century Partners (5CP) has sold Radon Medical Imaging to Leonard Green & Partners after Radon more than tripled revenue and grew from five states to 26 during the four-year hold. The parties did not disclose financial terms.

Radon scaled from a regional servicer to a 26-state platform under 5CP

5CP invested in Radon in 2022. Radon now employs more than 220 people, including over 135 field service technicians and engineers. The Charleston, West Virginia-based company services, repairs, assembles and sells new and refurbished imaging equipment, including MRI, PET/CT, mammography, cardiac cath lab and C-arm systems.

SALT LAKE CITY – October 28, 2026 -- Thorne converted 80% of its paper batch records to electronic batch records (EBR) in 2026 using MasterControl Manufacturing Excellence (Mx), earning the Manufacturing Excellence Award at MasterControl's 2026 Masters Summit. The October event named four winners of the Masters of Excellence Awards, which recognize MasterControl customers in quality management, manufacturing, asset excellence and innovation.

Thorne targets full electronic batch record rollout by year-end

Thorne aims to complete its EBR implementation by the end of 2026, with MasterControl Logbooks planned next. After five years on MasterControl, the company reports measurable gains in right-first-time rates, record review and release times, and quality performance.

Nashville – October 28, 2026 -- RevSpring's conversational AI agent Let's Talk lifted patient payment rates by 36% in initial customer deployments while cutting transfers to live agents by 27%, the healthcare payments provider said as it added phone-based payment plan setup to the product.

Let's Talk sets up payment plans by phone using the PersonaPay decisioning engine

The intelligent virtual agent is integrated with PersonaPay, RevSpring's Best in KLAS patient payment portal. Both run on the same decisioning engine, so payment plan options reflect what each patient can afford and stay consistent across voice, digital and staff-assisted channels.

Portland – October 28, 2026 -- Postpartum Support International (PSI) has launched a legal justice program backed by $120,000 in new funding, led by a $100,000 "Decriminalizing Mental Illness" grant from the Sozosei Foundation, the philanthropic arm of healthcare company Otsuka. Two $10,000 gifts from private donors complete the funding.

The program trains attorneys and other legal professionals, prepares perinatal mental health specialists to act as expert witnesses, and supports women and families drawn into the legal system because of perinatal mental illness. PSI says unrecognized or misunderstood conditions in criminal, family or employment proceedings can separate families, end careers and lead to incarceration.

PSI President and CEO Wendy Davis said nowhere are the consequences of that misunderstanding greater than in a courtroom.

WASHINGTON – October 28, 2026 -- Vanda Pharmaceuticals (Nasdaq: VNDA) reported that NEREUS (tradipitant) cut the incidence of semaglutide-induced vomiting by 27% in a Phase III trial. Vomiting occurred in 43.0% of treated participants (61/142) versus 58.5% on placebo (96/164), with a p-value of 0.006.

The company plans to discuss the data with the U.S. Food and Drug Administration (FDA). It intends to file a supplemental New Drug Application (sNDA) for preventing vomiting associated with GLP-1 receptor agonist therapy.

NEREUS lowers combined vomiting and severe nausea by 35% in key secondary endpoint

The key secondary endpoint combined any vomiting with worst nausea of 3 or higher. It occurred in 33.1% of participants on NEREUS (47/142) versus 50.6% on placebo (83/164), a 35% relative reduction (p=0.002).

Cambridge, Mass. – October 28, 2026 -- CREATE Medicines will present preclinical data showing complete B cell depletion in lymph nodes, spleen and bone marrow after low doses of its in vivo CAR-T therapy at the APLAR 2026 Congress in Seoul, running October 28 to November 1 at the COEX Convention & Exhibition Center.

Adam Raff presents mouse and primate data on October 31

Adam Raff, MD, PhD, SVP of Autoimmune Clinical Development, will deliver the oral abstract "In Vivo Generation of CAR-T Cells for the Treatment of B-cell Mediated Autoimmune Disease" in Abstract Session 2. The data come from mice and non-human primates. They show that low doses cleared B cells from the deep tissues where autoimmune disease takes hold.

INDIANAPOLIS – October 28, 2026 -- Carnyx Therapeutics has advanced its lead oral sleep candidate, CNYX-005, into Investigational New Drug (IND)-enabling development, bringing the preclinical asset closer to potential first-in-human studies.

Aged-rat data show 1.5 to 2 hours of added sleep

In recently reported preclinical findings, CNYX-005 increased total sleep time by roughly 1.5 to 2 hours versus controls in aged rats. The gain was driven primarily by increased non-rapid eye movement (NREM) sleep. Chief Medical Officer Chris Brearley said existing treatments are limited by safety, tolerability and long-term use concerns, which he cited as the case for additional options.