Ingenix's 9B Model Tops LongevityBench, Beating Claude Opus 4.6
Warsaw – November 09, 2026 -- Ingenix's "Thalamus Reasoning" model ranks first among 29 models on LongevityBench, the independent benchmark for language models in cellular aging research, with a mean rank of 1.42 across the benchmark's 14 ranked tasks. The next best model scores 4.42. The best frontier model, Claude Opus 4.6, scores 9.85.
Ingenix's 9-billion-parameter model wins 11 of 14 benchmark tasks
The model was built by a small team and outperforms 28 published models, including systems from leading frontier labs. It also beats the best non-LLM baseline on eight tasks.
On DNA methylation age prediction, Thalamus Reasoning posts an error of 3.36 years. The best text-prompted model on the same Qwen3.5-9B base scores 12.9 years, and the Horvath clock scores 4.67 years. On transcriptomics ordering, the model reaches 0.828 accuracy against 0.671 for the best other LLM.