Truveta Data

United States – October 29, 2026 -- Influenza-associated hospitalizations reached 3.5 per 1,000 hospitalizations in the week beginning September 21, 2026, nearly three times the next-highest rate recorded at the same point in the prior six flu seasons, according to a Truveta Data analysis.

Hospitalization rate climbs more than 2.5 times faster than in any prior season

From the week beginning August 31 through the week beginning September 21, the rate rose by an average of 0.7 hospitalizations per 1,000 each week. The next-fastest increase over the comparable period was 0.3 per 1,000 per week, in 2022–23.

Across the six prior seasons, the median weekly change at this point was −0.03 per 1,000. Hospitalization rates were generally stable or declining at this stage of past seasons.

United States – October 29, 2026 -- High-dose loop diuretics combined with adjuvant therapy produced an adjusted average weight loss of 4.6 pounds in heart failure inpatients, the largest of any strategy, but also came with higher rates of acute kidney injury, according to a study in the Journal of Cardiac Failure.

Study tracks 109,000 heart failure patients across US health systems

Researchers used Truveta Data to identify more than 109,000 patients hospitalized for heart failure between 2015 and 2022. Patients were grouped by the most intensive diuretic strategy used within the first 48 hours, ranging from low-dose loop diuretics alone to high-dose loop diuretics combined with thiazides or acetazolamide.

The team measured weight loss, hemoconcentration, in-hospital acute kidney injury, and the combined outcome of readmission or death within 90 days.

United States – October 27, 2026 -- Robotic assistance in total knee arthroplasty (TKA) rose from 12.4% of procedures in 2018 to 36.1% in 2026, a 191% relative increase, according to an analysis of 362,667 procedures in Truveta Data.

Robotic assistance was used in 24.3% of all procedures in the study period, which ran from January 2018 to August 2026. Robotic-assisted cases ran longer. Median operation time was 136 minutes (IQR 116-160), against 126 minutes (IQR 109-149) without robotics.